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MicroRNA Interference Technologies
Language: en
Pages: 194
Authors: Zhiguo Wang
Categories: Science
Type: BOOK - Published: 2009-06-11 - Publisher: Springer Science & Business Media

MicroRNAs (miRNAs), endogenous noncoding regulatory mRNAs of around 22-nucleotides long, have rapidly emerged as one of the key governors of the gene expression regulatory program in cells of varying species, with ever-increasing implications in the control of the fundamental biological processes and in the pathogenesis of adult humans. The exciting
Cancer and Noncoding RNAs
Language: en
Pages: 576
Authors: Jayprokas Chakrabarti, Sanga Mitra
Categories: Medical
Type: BOOK - Published: 2017-10-13 - Publisher: Academic Press

Cancer and Noncoding RNAs offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and
RNA Technologies and Their Applications
Language: un
Pages: 452
Authors: Volker A. Erdmann, Jan Barciszewski
Categories: Medical
Type: BOOK - Published: 2010-09-02 - Publisher: Springer Science & Business Media

RNA technologies are the driving forces of modern medicine and biotechnology. They combine the fields of biochemistry, chemistry, molecular biology, cell biology, physics, nanotechnology and bioinformatics. The combination of these topics is set to revolutionize the medicine of tomorrow. After more than 15 years of extensive research in the field
RNA Interference from Biology to Therapeutics
Language: un
Pages: 340
Authors: Kenneth A. Howard
Categories: Medical
Type: BOOK - Published: 2012-10-19 - Publisher: Springer Science & Business Media

The enormous potential of siRNA as a therapeutic has led to an explosion of interest from the scientific community. There has been intense interest from Big Pharma to capitalise on this new technology but the fact remains that delivery is a key determinant in realizing the full clinical potential of
Rnai Technologies
Language: un
Pages: 377
Authors: Prerna Pandey
Categories: Medical
Type: BOOK - Published: 2017-11 - Publisher: Delve Publishing

RNA interference (RNAi), one of the most exciting discoveries of the last decade, is also known as Post-Transcriptional Gene Silencing (PTGS). It is a conserved host defense response via double-stranded RNA against both endogenous and foreign nucleic acids, and occurs at the levels of transcription, post-transcription and translation. RNA induced